Current Issue April 2012, Vol. 163, No. 4

Issue Highlights

Target temperature management after out-of-hospital cardiac arrest—a randomized, parallel-group, assessor-blinded clinical trial—rationale and design
April 2012 (Vol. 163 | No. 4 | Pages 541-548)
Niklas Nielsen, Jørn Wetterslev, Nawaf al-Subaie, Bertil Andersson, John Bro-Jeppesen, Gillian Bishop, Iole Brunetti, Julius Cranshaw, Tobias Cronberg, Kristin Edqvist, David Erlinge, Yvan Gasche, Guy Glover, Christian Hassager, Janneke Horn, Jan Hovdenes, Jesper Johnsson, Jesper Kjaergaard, Michael Kuiper, Jørund Langørgen, Lewis Macken, Louise Martinell, Patrik Martner, Thomas Pellis, Paolo Pelosi, Per Petersen, Stefan Persson, Malin Rundgren, Manoj Saxena, Robert Svensson, Pascal Stammet, Anders Thorén, Johan Undén, Andrew Walden, Jesper Wallskog, Michael Wanscher, Matthew P. Wise, Nicholas Wyon, Anders Åneman, Hans Friberg
Reinfarction after percutaneous coronary intervention or medical management using the universal definition in patients with total occlusion after myocardial infarction: Results from long-term follow-up of the Occluded Artery Trial (OAT) cohort
April 2012 (Vol. 163 | No. 4 | Pages 563-571)
Harvey D. White, Harmony R. Reynolds, Antonio C. Carvalho, Camille A. Pearte, Li Liu, C. Edwin Martin, Genell L. Knatterud, Vladimír Džavík, Mariusz Kruk, Philippe Gabriel Steg, Warren J. Cantor, Venu Menon, Gervasio A. Lamas, Judith S. Hochman
Exercise intervention and inflammatory markers in coronary artery disease: A meta-analysis
April 2012 (Vol. 163 | No. 4 | Pages 666-676.e3)
Walter Swardfager, Nathan Herrmann, Stephen Cornish, Graham Mazereeuw, Susan Marzolini, Lauren Sham, Krista L. Lanctôt

Cardiogenic shock complicating acute coronary syndromes: Insights from the Global Registry of Acute Coronary Events
11 May 2012
Hamza H. Awad, Frederick A. Anderson, Joel M. Gore, Shaun G. Goodman, Robert J. Goldberg
Introduction: Despite advances in the management of patients with an acute coronary syndrome (ACS), cardiogenic shock (CS) remains the leading cause of death in these patients. The objective of this o...
B-type natriuretic peptide level and postdischarge thrombotic events in older patients hospitalized with heart failure: Insights from the Acute Decompensated Heart Failure National Registry
11 May 2012
Robb D. Kociol, Melissa A. Greiner, Bradley G. Hammill, Zubin J. Eapen, Gregg C. Fonarow, Winslow Klaskala, Roger M. Mills, Lesley H. Curtis, Adrian F. Hernandez
Background: Patients hospitalized with heart failure (HF) have elevated B-type natriuretic peptide (BNP) levels and increased risk for thromboembolic events. Associations between BNP level and thrombo...
Design and rationale of a retrospective clinical effectiveness study of aldosterone antagonist therapy in patients with heart failure
11 May 2012
Lesley H. Curtis, Xiaojuan Mi, Laura G. Qualls, Bradley G. Hammill, Stephen C. Hammill, Paul A. Heidenreich, Frederick A. Masoudi, Soko Setoguchi, Adrian F. Hernandez, Gregg C. Fonarow
Background: Despite demonstrated efficacy in randomized trials, aldosterone antagonist therapy is not used in many eligible patients with heart failure. Questions remain about its clinical effectivene...
Methodologies to characterize the QT/corrected QT interval in the presence of drug-induced heart rate changes or other autonomic effects
07 May 2012
Christine E. Garnett, Hao Zhu, Marek Malik, Anthony A. Fossa, Joanne Zhang, Fabio Badilini, Jianguo Li, Börje Darpö, Philip Sager, Ignacio Rodriguez
This White Paper, written collaboratively by members of the Cardiac Safety Research Consortium from academia, industry, and regulatory agencies, discusses different methods to characterize the QT effe...
The SPIRIT V Diabetic Study: A randomized clinical evaluation of the XIENCE V everolimus-eluting stent vs the TAXUS Liberté paclitaxel-eluting stent in diabetic patients with de novo coronary artery lesions
12 April 2012
Eberhard Grube, Bernard Chevalier, Giulio Guagliumi, Peter C. Smits, Marrianne Stuteville, Cécile Dorange, Peggy Papeleu, Upendra Kaul, Vladimír Džavík
Background: Diabetic patients respond less favorably to revascularization and have poorer long-term outcomes. Our main aim was to evaluate the angiographic efficacy of XIENCE V (everolimus-eluting ste...

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Efficacy of exercise-based cardiac rehabilitation post–myocardial infarction: A systematic review and meta-analysis of randomized controlled trials
October 2011 (Vol. 162 | No. 4 | Pages 571-584.e2)
Patrick R. Lawler, Kristian B. Filion, Mark J. Eisenberg
Rationale and design of RE-LY: Randomized evaluation of long-term anticoagulant therapy, warfarin, compared with dabigatran
May 2009 (Vol. 157 | No. 5 | Pages 805-810.e2)
Michael D. Ezekowitz, Stuart Connolly, Amit Parekh, Paul A. Reilly, Jeanne Varrone, Susan Wang, Jonas Oldgren, Ellison Themeles, Lars Wallentin, Salim Yusuf
Study of Heart and Renal Protection (SHARP): Randomized trial to assess the effects of lowering low-density lipoprotein cholesterol among 9,438 patients with chronic kidney disease
November 2010 (Vol. 160 | No. 5 | Pages 785-794.e10)
SHARP Collaborative Group
Rationale and design of the Anti-Xa Therapy to Lower cardiovascular events in Addition to standard therapy in Subjects with Acute Coronary Syndrome–Thrombolysis in Myocardial Infarction 51 (ATLAS-ACS 2 TIMI 51) trial: A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of rivaroxaban in subjects with acute coronary syndrome
May 2011 (Vol. 161 | No. 5 | Pages 815-821.e6)
C. Michael Gibson, Jessica L. Mega, Paul Burton, Shinya Goto, Freek Verheugt, Christoph Bode, Alexei Plotnikov, Xiang Sun, Nancy Cook-Bruns, Eugene Braunwald
Newest-generation drug-eluting and bare-metal stents combined with prasugrel-based antiplatelet therapy in large coronary arteries: The BAsel Stent Kosten Effektivitäts Trial PROspective Validation Examination part II (BASKET-PROVE II) trial design
February 2012 (Vol. 163 | No. 2 | Pages 136-141.e1)
Raban Jeger, Matthias Pfisterer, Hannes Alber, Franz Eberli, Søren Galatius, Christoph Naber, Giovanni Pedrazzini, Hans Rickli, Jan Skov Jensen, André Vuilliomenet, Nicole Gilgen, Christoph Kaiser

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About American Heart Journal

American Heart Journal has been a trusted resource for cardiologists and general practice physicians for more than 80 years. The Journal focuses its content to respond to the information needs of the cardiology community. In addition to publishing results of important clinical investigations, the Journal addresses such topics as cost-effectiveness, design of clinical trials, reports of negative clinical trials, and the changing organization of medical care.

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Transradial Angiography and Intervention Focus Issue: Call for Papers

In recognition of the increasing interest and adoption of transradial angiography and intervention, the American Heart Journal will publish a special section dedicated to transradial invasive procedures, in the September 2012 issue. Studies that will be considered for publication include observational analyses or randomized trials that examine technical issues, implementation, or outcomes. Manuscripts should be submitted by June 30, 2012.

To submit your manuscript and for Instructions to Authors, visit http://ees.elsevier.com/ahj/.

For further information, contact Guest Editor Sunil Rao, MD, at sunil.rao@dm.duke.edu.

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